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Index > Protein center > Aicda(Gene name) > Mouse
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  • Aicda (Gene name),
  • Activation-induced cytidine deaminase (Protein name ),  AICDA_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Aicda(Aid);
    Protein name:
    Activation-induced cytidine deaminase;
    Alternative:
    Cytidine aminohydrolase;Cytidine aminohydrolase;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Single-stranded DNA-specific cytidine deaminase. Involved in somatic hypermutation, gene conversion, and class-switch recombination in B-lymphocytes. Required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses. May also play a role in the epigenetic regulation of gene expression by participating to DNA demethylation.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    198
    Sequence:
    50:
    MDSLLMKQKK | FLYHFKNVRW | AKGRHETYLC | YVVKRRDSAT | SCSLDFGHLR | 
    100:
    NKSGCHVELL | FLRYISDWDL | DPGRCYRVTW | FTSWSPCYDC | ARHVAEFLRW | 
    150:
    NPNLSLRIFT | ARLYFCEDRK | AEPEGLRRLH | RAGVQIGIMT | FKDYFYCWNT | 
    198:
    FVENRERTFK | AWEGLHENSV | RLTRQLRRIL | LPLYEVDDLR | DAFRMLGF
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    String:
    UniGene:
    KEGG:
    Pfam:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Activation-induced cytidine deaminase
    Cat.:
    E14184d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse Activation-induced cytidine deaminase
    Cat.:
    E14184h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse Activation-induced cytidine deaminase
    Cat.:
    E14184m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Mouse Activation-induced cytidine deaminase
    Cat.:
    E14184b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Activation-induced cytidine deaminase
    Cat.:
    U14184d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Activation-induced cytidine deaminase
    Cat.:
    U14184h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Activation-induced cytidine deaminase
    Cat.:
    U14184m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Activation-induced cytidine deaminase
    Cat.:
    U14184b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Activation-induced cytidine deaminase
    Cat.:
    P14184Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Activation-induced cytidine deaminase
    Cat.:
    P14184Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Activation-induced cytidine deaminase
    Polyclonal Antibody for Mouse Activation-induced cytidine deaminase
    Monoclonal Antibody for Mouse Activation-induced cytidine deaminase
    Monoclonal Antibody for Mouse Activation-induced cytidine deaminase
    Monoclonal Antibody for Mouse Activation-induced cytidine deaminase
    Monoclonal Antibody for Mouse Activation-induced cytidine deaminase
    Protein for Mouse Activation-induced cytidine deaminase
    Protein for Mouse Activation-induced cytidine deaminase
    Protein for Mouse Activation-induced cytidine deaminase
    Protein for Mouse Activation-induced cytidine deaminase

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells."
      Muramatsu M. , Sankaranand V.S. , Anant S. , Sugai M. , Kinoshita K. , Davidson N.O. , Honjo T.
      J. Biol. Chem.274:18470-18476(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Transcription-targeted DNA deamination by the AID antibody diversification enzyme."
      Chaudhuri J. , Tian M. , Khuong C. , Chua K. , Pinaud E. , Alt F.W.
      Nature422:726-730(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;MUTAGENESIS OF HIS-56 AND GLU-58
    3. 3.
      "Histone chaperone Spt6 is required for class switch recombination but not somatic hypermutation."
      Okazaki I.M. , Okawa K. , Kobayashi M. , Yoshikawa K. , Kawamoto S. , Nagaoka H. , Shinkura R. , Kitawaki Y. , Taniguchi H. , Natsume T. , Iemura S. , Honjo T.
      Proc. Natl. Acad. Sci. U.S.A.108:7920-7925(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SUPT6H; TRIM28 AND NCL
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