Protein name:
Activation-induced cytidine deaminase ;
Alternative:
Cytidine aminohydrolase ;Cytidine aminohydrolase ;
Organism:
Mouse (Mus musculus).
General Annotation
Function:
Single-stranded DNA-specific cytidine deaminase. Involved in somatic hypermutation, gene conversion, and class-switch recombination in B-lymphocytes. Required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses. May also play a role in the epigenetic regulation of gene expression by participating to DNA demethylation.
Subcellular Location:
N/A
Protein Attributes:
50:
MDSLLMKQKK | FLYHFKNVRW | AKGRHETYLC | YVVKRRDSAT | SCSLDFGHLR |
100:
NKSGCHVELL | FLRYISDWDL | DPGRCYRVTW | FTSWSPCYDC | ARHVAEFLRW |
150:
NPNLSLRIFT | ARLYFCEDRK | AEPEGLRRLH | RAGVQIGIMT | FKDYFYCWNT |
198:
FVENRERTFK | AWEGLHENSV | RLTRQLRRIL | LPLYEVDDLR | DAFRMLGF
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Dog
Human
Mouse
Bovine
ELISA Kit for Mouse Activation-induced cytidine deaminase
ELISA Kit for Mouse Activation-induced cytidine deaminase
ELISA Kit for Mouse Activation-induced cytidine deaminase
ELISA Kit for Mouse Activation-induced cytidine deaminase
CLIA Kit for Mouse Activation-induced cytidine deaminase
CLIA Kit for Mouse Activation-induced cytidine deaminase
CLIA Kit for Mouse Activation-induced cytidine deaminase
CLIA Kit for Mouse Activation-induced cytidine deaminase
Polyclonal Antibody for Mouse Activation-induced cytidine deaminase
Polyclonal Antibody for Mouse Activation-induced cytidine deaminase
Polyclonal Antibody for Mouse Activation-induced cytidine deaminase
Polyclonal Antibody for Mouse Activation-induced cytidine deaminase
Monoclonal Antibody for Mouse Activation-induced cytidine deaminase
Monoclonal Antibody for Mouse Activation-induced cytidine deaminase
Monoclonal Antibody for Mouse Activation-induced cytidine deaminase
Monoclonal Antibody for Mouse Activation-induced cytidine deaminase
Protein for Mouse Activation-induced cytidine deaminase
Protein for Mouse Activation-induced cytidine deaminase
Protein for Mouse Activation-induced cytidine deaminase
Protein for Mouse Activation-induced cytidine deaminase
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;MUTAGENESIS OF HIS-56 AND GLU-58
3.
"Histone chaperone Spt6 is required for class switch recombination but not somatic hypermutation."
Okazaki I.M.
,
Okawa K.
,
Kobayashi M.
,
Yoshikawa K.
,
Kawamoto S.
,
Nagaoka H.
,
Shinkura R.
,
Kitawaki Y.
,
Taniguchi H.
,
Natsume T.
,
Iemura S.
,
Honjo T.
Proc. Natl. Acad. Sci. U.S.A.108:7920-7925(2011)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH SUPT6H; TRIM28 AND NCL